教授，主任医师，硕士生导师，厦门大学附属第一医院内分泌糖尿病科行政副主任，

Email: liuchangqin@xmu.edu.cn

工作学习经历：

2003~2006 上海交通大学医学院内科学（内分泌代谢病） 医学博士；

2006-至今 厦门大学附属第一医院内分泌糖尿病科

2010-2012 美国西北太平洋糖尿病研究所（PNDRI） 博士后；

2012-2013 美国华盛顿大学医学院 访问学者

研究方向：

1）肥胖及相关疾病（PCOS、NAFLD、IGR、OSAS）的临床和基础研究

2）2型糖尿病的临床及基础研究

学术兼职：

中华中医药学会糖尿病分会常委兼秘书长

中华医学会内分泌学分会电解质紊乱学组（筹）委员

福建省海医会内分泌代谢病分会副会长

福建省医师协会内分泌代谢科医师分会委员

福建省糖尿病学分会肥胖学组秘书

厦门内分泌代谢科医师分会常委兼秘书长

厦门市内分泌学分会委员

代表性成果：

1. Chen Y#; Zheng X#; Ma D; Zheng S; Han Y; Su W; Liu W; Xiao F; Lin M; Yan X; Zhao T; Liu C*; Neck circumference is a good predictor for insulin resistance in women with polycystic ovary syndrome. Fertil Steril. 2021;115(3):753-760.

2. Zheng X#; Chen Y#; Ma D; Zhang M; Huang Y; Tong M; Yan B; Lin S; Yan X*; Liu C*; Correlation Between Daily Energy Intake from Fat with Insulin Resistance in Patients with Polycystic Ovary Syndrome. Diabetes Metab Syndr Obes, 2021, 14: 295-303.

3. Su W#, Chen G#, Ma D, Zeng J, Yan F, Lin X, Xu Z, Yang S, Li Z*, Liu C*. Higher Apnea-Hypopnea Index (AHI) and Oxygen Desaturation Index (ODI) Were Independently Associated with Increased Risks of Hypertension in Patients with T2DM: A Cross-Sectional Study. Int J Hypertens. 2021; 2021:8887944.

4. Zheng S#, Tong M#, Dong L, Du C, Zheng X, Wang L, Huang P, Liu W, Lin M, Liu C*. Lipid accumulation product independently correlate with hepatic steatosis quantified by controlled attenuation parameter in women with polycystic ovary syndrome. Endocr Connect 2020; 9:154-162.

5. Dong L#, Lin M#, Wang W#, Ma D, Chen Y, Su W, Chen Z, Wang S, Li X, Li Z*, Liu C*. Lipid accumulation product (LAP) was independently associatedwith obstructive sleep apnea in patients with type 2 diabetes mellitus. BMC Endocr Disord. 2020; 20:179.

6. Du C#, He C#, Dong L, Zheng S, Wang W, Zheng C, Wang S, Lin M, Yang S, Li X, Li Z*, Liu C*. Associations of apnea hypopnea index and educational attainments with microvascular complications in patients with T2DM. Endocrine 2020; 67:363-373.

7. Ma D#, Zheng X#, Dong L, Zheng C, Chen Y, Chen Z, Lin M, Li X, Li Z*, Liu C*. The Relationship of Serum 25-Hydroxyvitamin-D Level with Severity of Obstructive Sleep Apnea in Patients with Type 2 Diabetes Mellitus. Diabetes Metab Syndr Obes. 2020; 13:1391-1398.

8. Zheng C#, Song H#, Wang S, Liu J, Lin T, Du C, Xie H, Chen Z, Zheng S, Li Z, Li X, Liu C*. Serum Uric Acid Is Independently Associated with Risk of Obstructive Sleep Apnea-Hypopnea Syndrome in Chinese Patients with Type 2 Diabetes. Dis Markers 2019:4578327.

9. Lin M#, Liu C#, Liu Y, Wang D, Zheng C, Shi X, Chen Z, Liu J, Li X, Yang S*, Li Z*. Fetuin-B Links Nonalcoholic Fatty Liver Disease to Chronic Kidney Disease in Obese Chinese Adults: A Cross-Sectional Study. Ann Nutr Metab 2019; 74:287-295.

10. Li Z#, Lin M#, Liu C#, Chen Z, Wang D, Shi X, Yang S, Li XJ*. The rs4686434 variant in the fetuin B (FETUB) locus is associated with intrahepatic triglyceride content in obese Chinese adults. J Diabetes 2018; 10:916-925.

11. Liu Y#, Liu C#, Shi X, Lin M, Yan B, Zeng X, Chen N, Lu S, Liu S, Yang S, Li X, Li Z*. Correlations of non-alcoholic fatty liver disease and serum uric acid with subclinical atherosclerosis in obese Chinese adults. J Diabetes 2017; 9:586-595.

12. Li Z#, Liu C#, Shi X, Chen Z, Wang D, Li L, Tu Y, Lin M, Liu S, Yang S*, Li X*. Common genetic variants in the FETUB locus, genetically predicted fetuin-B levels, and risk of insulin resistance in obese Chinese adults. Medicine (Baltimore) 2017; 96: e9234.

13. Liu CQ#, He CM#, Chen N, Wang D, Shi X, Liu Y, Zeng X, Yan B, Liu S, Yang S, Li X, Li X*, Li Z*. Serum uric acid is independently and linearly associated with risk of nonalcoholic fatty liver disease in obese Chinese adults. Sci Rep 2016; 6:38605.

14. Liu C#, Cholerton B#, Shi M, Ginghina C, Cain KC, Auinger P, Parkinson Study Group DI, Zhang J*. CSF tau and tau/Abeta42 predict cognitive decline in Parkinson's disease. Parkinsonism Relat Disord 2015; 21:271-276.

15. Jia H#, Tao F#, Liu C#, Guo T, Zhu W, Wang S, Cui B, Ning G*. Both interleukin-23A polymorphism and serum interlukin-23 expression are associated with Graves' disease risk. Cell Immunol 2015; 294:39-43.

16. Stewart T#, Liu C#, Ginghina C, Cain KC, Auinger P, Cholerton B, Shi M, Zhang J*, Parkinson Study Group DI. Cerebrospinal fluid alpha-synuclein predicts cognitive decline in Parkinson disease progression in the DATATOP cohort. Am J Pathol 2014; 184:966-975.

17. Shi M#, Liu C#, Cook TJ, Bullock KM, Zhao Y, Ginghina C, Li Y, Aro P, Dator R, He C, Hipp MJ, Zabetian CP, Peskind ER, Hu SC, Quinn JF, Galasko DR, Banks WA, Zhang J*. Plasma exosomal alpha-synuclein is likely CNS-derived and increased in Parkinson's disease. Acta Neuropathol 2014; 128:639-650.

18. Mahadevan J#, Parazzoli S, Oseid E, Hertzel AV, Bernlohr DA, Vallerie SN, Liu CQ, Lopez M, Harmon JS, Robertson RP*. Ebselen treatment prevents islet apoptosis, maintains intranuclear Pdx-1 and MafA levels, and preserves beta-cell mass and function in ZDF rats. Diabetes 2013; 62:3582-3588.

19. Zhang W#, Liu CQ#, Wang PW, Sun SY, Su WJ, Zhang HJ, Li XJ, Yang SY*. Puerarin improves insulin resistance and modulates adipokine expression in rats fed a high-fat diet. Eur J Pharmacol 2010; 649:398-402.

20. Liu CQ#, Li XJ, Zhang W, Zhang HJ, Lin MZ, Yang SY*. Immediate but not long-term administration of nicardipine inhibits tolbutamide-induced insulin secretion from rat pancreatic beta cells. Pancreas 2010; 39:452-457.

主持课题：

1. 国家自然科学基金面上项目:NO. 81870611, 2019-2022；  

2. 福建省自然科学基金面上项目：NO. 2020J011242, 2020-2023

3. 福建省自然科学基金面上项目: NO. 2015J01555, 2015 -2018；

4. 厦门市科技计划项目: NO. 3502Z20154010, 2015-2018；

5. 福建省科技厅杰出青年基金: NO. 2009D016, 2010-2012；

6. 福建省卫生厅青年科研课题: NO. 2008-2-38, 2008-2011；

7. 厦门市科技计划项目: NO.3502Z20077050, 2007-2009

荣 誉：

2007年 厦门市卫生系统学术与技术带头人后备人才；

2008年 厦门大学附属第一医院先进工作者；

2014年 厦门大学附属第一医院年度“十佳医生”；

2014年 厦门市卫生系统优秀教育工作者；

2015年 厦门大学医学院教学工作先进个人；

2018年 厦门大学附属第一医院年度“优秀教师”