吉国力  教授，博士生导师

研究方向：健康大数据分析，工业建模与控制、智能计算方法与物联网平台开发

联系电话：

电子邮箱：glji@ xmu.edu.cn

个人简介

目前本人主要研究先进控制、生医信息、数据挖掘及信息系统，研究需求主要来自美国、加拿大等国际前沿。作为学者多次短期学习和交流访问过澳大利亚、加拿大、美国和荷兰等10多所大学，与国际建立了多条常态合作研究渠道，近期又引发德国、美国等多所大学合作要求。本人近年努力开展国际合作，坚持向自然学习和为学生服务的观点，鼓励并用心帮助学生有意识成为世界的中国人，积极开拓与国外高校多方资助联合培养在校生，为学生创造多渠道高层次培养机会。总体上，近年在国际合作、科研成果、队伍建设、基金申请、学生培养和学科建设多方面取得显著成效。

到目前已指导30多届本科毕业生达130多人，指导硕士与博士研究生及博士后达130多人，培养获博士学位学生14人、硕士学位100多人以及博士后出站和省优秀博士论文各1人。

近年提供本人指导学生有10+1人次去香港、3人次去韩国、15人次去美国、1人次去荷兰，2人次去澳大利亚、7+2+2人次去加拿大、2人次去土耳其和迪拜、2人次去泰国、2人次去马来西亚和泰国、5人次去台湾、1人次去意大利和西班牙、1人次去捷克和俄罗斯、2人次去泰国和印度、2人次去德国和挪威参加国际项目合作、会议和联合培养。近年本人已派送在学硕博研究生到美加欧（如美国Miami University、荷兰Eindhoven University of Technology、加拿大York University、加拿大University of Alberta、美国Texas A&M University、美国Mississippi State University、美国Washington State University、加拿大University of Toronto等）联合培养1年或以上的本人指导学生达20多人次，这些学生学成回国返校后在做事思维科研习惯生活态度各个方面明显成长并获得中国留学人员称号和享受相应国家待遇。另外也吸引了美国等国家大学生主动要求作为Intership来我们实验室进行短期学习以及国外学生硕士博士留学申请，扩大了国际影响。

已发表论文100多篇，其中JCR国际期刊上正式及接受发表论文80多篇，70多篇已被SCI收录(SCI引用830多次)、80多篇被EI收录；近年主持国家基金3项、博士点基金3项（1项优先发展领域）、省市及国际合作基金及科技项目10多项，近期还参与国家自然科学基金重大研究计划1项且获得国家重大专项1项(作为专题子项负责人)，还承担过大量企业应用项目。与荷兰Eindhoven University of Technology、荷兰Taiji Control、加拿大University of Alberta、加拿大York University主要合作研究先进控制的系统建模仿真与优化控制方法、模型预测控制、多变量过程辨识、大型工业的远程控制系统、模型诊断与故障诊断方法、数据挖掘方法等且部分研发成果已应用于国际市场，合作获得了国家自然科学基金、福建省重点科技项目、福建省自然科学基金、厦门市重点科技项目、国际合作和企业创新项目等资助，合作发表SCI收录论文16篇及IFAC会议上发表3篇，近期代表性成果发表在IEEE Transactions on Industrial Electronics(2013IF=6.500)、Journal of Process Control、IEEE Transactions on Systems Man and Cybernetics Part C: Applications and Reviews、IEEE Transactions on Human-Machine Systems、Knowledge-based Systems、Chemometrics and Intelligent Laboratory Systems上；还与美国和加拿大有多所大学合作研究自然对象的动态机制建模仿真、高维数据特征选择方法、生医信息的识别与处理、基因适应性与疾病关联分析以及大量模式分析和数据挖掘的现实问题，已合作获得基金10多项（国家自然科学基金4项、高校博士学科点专项科研基金4项和福建省自然科学基金2项等），合作发表30多篇JCR国际期刊论文，代表性成果发表在PNAS(美国科学院院刊，2010IF=9.771)、Genome Research(2010IF=13.588)、Plant Cell(2011IF=8.987)、Cell Research(2010IF=9.417)、Plos Genetics(2013IF=8.167)、Bioinformatics(2016IF=7.307)等顶级国际期刊上。

论文发表：

(1) AStrap: identification of alternative splicing from transcript sequences without a reference genome，Bioinformatics, 2019,xx(xx):xxxx-xxxx(SCI,2017IF=5.481, 06-Dec-2018 accepted) doi:10.1093/bioinformatics/bty1008，2019年06月

(2) Distinct genome-wide alternative polyadenylation during the response to silicon availability in the marine diatom Thalassiosira pseudonana，Plant Journal, 2019,xx(xx):xxxx–xxxx (SCI,2017IF=5.775, accepted:27 Feb.2019) doi:10.1111/tpj.14309，2019年03月

(3) Alternative Polyadenylation Coordinates Embryonic Development, Sexual Dimorphism and Longitudinal Growth in Xenopus tropicalis，Cellular and Molecular Life Sciences,2019,xx(xx):xxx-xxx (SCI,2017IF=6.721, accepted:30 Jan.2019) doi:10.1007/s00018-019-03036-1，2019年02月

(4) Genome-wide comparative analyses of polyadenylation signals in eukaryotes suggest a possible origin of the AAUAAA signal，International Journal of Molecular Science, 2019,20:958(SCI,2017IF=3.687, Accepted: 19 Feb.2019) doi:10.3390/ijms20040958，2019年02月

(5) Differential alternative polyadenylation contributes to the developmental divergence between two rice subspecies，Plant Journal, 2019,xx(xx):xxxx–xxxx (SCI,2017IF=5.775, accepted:06 Dec.2018) doi: 10.1111/tpj.14209，2019年02月

(6) Cluster analysis of replicated alternative polyadenylation data using canonical correlation analysis，BMC Genomics, 2019, 20-75 (SCI,2017IF=3.730).doi:10.1186/s12864-019-5433-7，2019年01月

(7) Prediction of DNA-binding proteins by interaction fusion feature representation and selective ensemble，Knowledge-based Systems, 2019, 163: 598-610.(SCI,2017IF=4.396, Accepted:13 Sep.2018) doi:10.1016/j.knosys.2018.09.023，2019年01月

(8) Partial Maximum Correlation Information: A new feature selection method for microarray data classification，Neurocomputing, 2019,323:231-243(SCI,2017IF=3.241, 02-Oct-2018 accepted) doi:10.1016/j.neucom.2018.09.084，2019年01月

(9) TSAPA: identification of tissue-specific alternative polyadenylation sites in plants，Bioinformatics, 2018,34(12)(SCI,2016IF=7.307, 23-Jan-2018 accepted) doi:10.1093/bioinformatics/bty044，2018年09月

(10) APAtrap: identification and quantification of al-ternative polyadenylation sites from RNA-seq data，Bioinformatics, 2018,34(11):1841-1849(SCI,2016IF=7.307, 18-Jan-2018 accepted) doi:10.1093/bioinformatics/bty029，2018年06月

(11) A Novel Feature Selection Method to Predict Protein Structural Class，Computational Biology and Chemistry, 2018,76:118-129(SCI,2016IF=1.331, 30-Jun-2018 accepted) doi:10.1016/j.compbiolchem.2018.06.007，2018年06月

(12) Research on A Reduced Order Closed-loop Identification algorithms Based on AIC for Process with Time Delay，Cluster Computing, 2018,7:1-14(SCI,2016IF=2.040, 12-Jan-2018 accepted) doi:10.1007/s10586-018-1843-6，2018年05月

(13) Alternative polyadenylation drives genome-to-phenome information detours in the AMPKα1 and AMPKα2 knockout mice，Scientific Reports, 2018.8:6462(SCI, 2017IF=4.259, 07-Apr-2018 accepted) doi:10.1038/s41598-018-24683-7，2018年04月

(14) AEGS: identifyingaberrantly expressed gene sets for differential variability analysis，Bioinformatics, 2018,34(5)(SCI,2016IF=7.307, 10-Oct-2017 accepted) doi:10.1093/bioinformatics/btx646，2018年03月

(15) Robust Adaptive Tracking Control for Manipulators Based on TSK Fuzzy Cerebellar Model Articulation Controller，IEEE Access, 2017,6:1670-1679(SCI,2016IF=3.244, 10-Nov-2017 accepted) doi:10.1109/ACCESS.2017.2779940，2017年12月

(16) Laser-Induced Breakdown Spectroscopy for Rapid Discrimination of Heavy-Metal-Contaminated Seafood Tegillarca Granosa，Sensors.2017,11:2655(SCI,2016IF=2.677, 5-Nov-2017 accepted) doi:10.3390/s17112655，2017年11月

(17) Bayesian Hybrid State Estimation for Unequal-length Batch Processes with Incomplete Observations，International Journal of Control, Automation and Systems,15(6):2480-2491 (SCI,2015IF=1.219, Accepted:18 Feb.2017) doi:10.1007/s12555-015-0444-x，2017年11月

(18) PAcluster: clustering polyadenylation site data using canonical correlation analysis，Journal of Bioinformatics and Computational Biology, 2017,15(5):1750018(19p)(SCI,2016IF=0.785, Accepted: 2 Aug.2017) doi:10.1142/S0219720017500184，2017年09月

(19) Integrating multiple fitting regression and Bayes decision for cancer diagnosis with transcriptomic data from tumor-educated blood platelets，Analyst, 2017,142:3588-3597(SCI,2016IF=3.885, Accepted: 14 Aug.2017) doi:10.1039/C7AN00944E，2017年09月

(20) Synchronized Bayesian state estimation in batch processes using a two-dimensional particle filter，Chemical Engineering Research and Design, 2017,125:9-23(SCI,2016IF=2.538, Accepted:4 Jul.2017) doi:10.16/j.cherd.2017.06.033，2017年07月

(21) Fast bias-constrained optimal FIR filtering for time-invariant state space models，International Journal of Adaptive Control and Signal Processing, 2017,31(7):1061-1076(SCI,2015IF=1.368, Accepted:11 Nov.2016) doi:10.1002/acs.2747，2017年07月

(22) An innovative one-class least squares support vector machine model based on continuous cognition，Knowledge-Based Systems,123:217-228.(SCI,2015IF=4.148, Accepted:20 Feb.2017) doi:10.1016/j.knosys.2017.02.024，2017年03月

(23) Feature Selection by Maximizing Correlation Information for Integrated High-dimensional Protein Data ，Pattern Recognition Letters,92:17-24(SCI,2015IF=1.586, Accepted:10 Mar.2017) doi:10.1016/j.patrec.2017.03.011，2017年03月

(24) Genome-wide Dynamics of Alternative Polyadenylation in Rice，Genome Research, 2016,26(12):1753-1760(SCI,2015IF=11.351) doi:10.1101/gr.210757.116，2016年12月

(25) Breast Tumor Computer-aided Diagnosis Using Self-Validation Cerebellar Model Neural Networks，Acta Polytechnica Hungarica, 2016,13(4):39-52(SCI,2015IF=0.544) doi:10.12700/APH.13.4.2016.4.3，2016年09月

(26) Aging shapes the population-mean and -dispersion of gene expression in human brains，Frontiers in Aging Neuroscience,2016,8(183)(SCI,2015IF=4.348, Accepted:15 Jul.2016)，2016年08月

(27) Exploiting aberrant mRNA expression in autism for gene discovery and diagnosis，Human Genetics,2016.135:797-811(SCI,2015IF=5.138)，2016年06月

(28) detectMITE: A novel approach to detect miniature inverted repeat transposable elements in genomes，Scientific Reports,2016,6:19688(SCI,2014IF=5.578)，2016年01月

(29) Genome-wide identification and predictive modeling of polyadenylation sites in eukaryotes，Briefings in Bioinformatics,2015,16(2):304-313(SCI, 2014IF=9.617)，2015年12月

(30) Multiple oscillations detection in control loops by using the DFT and Raleigh distribution，9th IFAC Symposium on Fault Detection, Supervision and Safety for Technical Processes, September 2, 2015 - September 4, 2015 Paris, France IFAC Proceedings Volumes 2015，48(21):529-534 (EI)，2015年09月

(31) Genome-wide characterization of intergenic polyadenylation sites redefines gene spaces in Arabidopsis thaliana，BMC Genomics,2015,16:511(SCI,2013IF=4.041)，2015年07月

(32) PlantOrDB: a genome-wide ortholog database for land plants and green algae，BMC Plant Biology,2015,15:161(SCI,2013IF=3.942)，2015年06月

(33) Using consensus interval partial least square in near infrared spectra analysis，Chemometrics and Intelligent Laboratory Systems,2015,144:56-62,doi:10.1016/j.chemolab.2015.03.008 (SCI, 2013IF=2.381,accepted: 21 Mar 2015)，2015年04月

(34) An Expectation Maximization Approach to Fault Diagnosis with Missing Data，IEEE Transactions on Industrial Electronics,2015,62(2):1231-1240, doi:10.1109/TIE.2014.2336635 (SCI, 2013IF=6.500,8-July-2014 online)，2015年02月

(35) PASPA: a web server for mRNA poly(A) site predictions in plants and algae，Bioinformatics.2015,(SCI,2013IF=4.621, 30-Dec-2014 accepted) ，2015年02月

(36) VAAPA: A web platform for visualization and analysis，Computers in Biology and Medicine, 2015.57:20-25 (SCI, 2013IF=1.534)，2015年01月

 

(37) Aberrant gene expression in humans，Plos Genetics,2015,15(1):e1004942 (SCI,2013IF=8.167)，2015年01月

(38) Computational analysis of plant polyadenylation signals，Methods in molecular biology, 2015,1255:3-11, doi:10.1007/978-1-4939-2175-1_1，2014年12月

(39) Prediction of plant mRNA polyadenylation sites，Methods in molecular biology, 2015, 1255:13-23 doi:10.1007/978-1-4939-2175-1_2，2014年12月

(40) Extraction of Poly(A) Sites from Large-Scale RNA-seq Data，Methods in molecular biology, 2015, 1255: 25-37 doi:10.1007/978-1-4939-2175-1_3，2014年12月

(41) Poly(A)-tag deep sequencing data processing to extract poly(a) sites，Methods in molecular biology, 2015, 1255: 39-48 doi:10.1007/978-1-4939-2175-1_4，2014年12月

(42) detectIR: A Novel Program for Detecting Perfect and Imperfect Inverted Repeats Using Complex Numbers and Vector Calculation，Plos One, 2014.9(11): e113349 (SCI, 2013IF=3.534)，2014年09月

(43) Gene expression responses of threespine stickleback to salinity:implications for salt-sensitive hypertension，Frontiers in Genetics, 2014,5:312 (SCI, 2013IF=1.794)，2014年09月

(44) Solving Partially Observable Problems with Inaccurate PSR Models，Information Sciences,2014,283:142-152 (SCI, 2013IF=3.893)，2014年06月

(45) Bioinformatics analysis of alternative polyadenylation in green alga Chlamydomonas reinhardtii using transcriptome sequences from three different sequencing platforms，G3: GENES, GENOMES, GENETICS,(SCI, 2012IF=1.794)，2014年03月

(46) Feature selection for high-dimensional multi-category data using PLS-based local recursive feature elimination，Expert Systems with Applications, 2014,41(4):1463-1475 (SCI, 2012IF=1.854)，2014年03月

(47) PLS-based recursive feature elimination for high-dimensional small sample，Knowledge-based Systems.2014,55(1):15-28 (SCI, 2012IF=4.104)，2014年03月

(48) A multiple sequence alignment method with sequence vectorization，Engineering Computations,2014,31(2):283-296 (SCI, 2012IF=1.214)，2014年03月

(49) TotalPLS: Local Dimension Reduction for Multicategory Microarray Data Analysis，IEEE Transactions on Human-Machine Systems, 2014,44(1):125-138 (SCI,2014IF=1.982)，2014年02月

(50) Two-level parallel alignment based on sequence parallel vectorization，Applied Mechanics and Materials, 2014, 490-491:757-762(Chapter 3: Engineering Design, Modeling, Simulation and Computational Methods) (EI) ，2014年01月

(51) Design and Implementation of an MPC System with Model Error Detection，2013 NIRMA UNIVERSITY INTERNATIONAL CONFERENCE ON ENGINEERING, NUiCONE-2013, 28-30 NOVEMBER, 2013,Ahmedabad,India (EI)，2013年11月

(52) A normalization method based on variance and median adjustment for massive mRNA polyadenylation data，BioTechnology : An Indian Journal,2013,8(4):518-522 (EI)，2013年10月

(53) ESAP: A new pipeline for genome wide identification of poly(A)-site-modifying SNPs in Arabidopsis，BioTechnology : An Indian Journal,2013,8(2):270-274 (EI)，2013年09月

(54) Advances in Mathematical Modeling and Simulation of DNA Replication Process，Current Bioinformatics. 2013,8(5):591-602(SCI, 2012IF=2.017)，2013年09月

(55) In silicon identification of DNA replication origin，IADIS 2013 European Conference on Data Mining, p 97-100, 2013, Prague, Czech Republic (EI)，2013年07月

(56) Identification and Predictive Control for a Circulation Fluidized Bed Boiler，Knowledge-Based Systems, 2013.45(6):62-75 (SCI,2012IF=4.104)，2013年06月

(57) Online Customer Interactive Web3D E-Commerce Platform NARKii.com，Applied Mathematics & Information Sciences, 2013,7(1):427-432 (SCI, 2011IF=0.508)，2013年01月

(58) LemK_MSA: A Multiple Sequence Alignment Method with Sequence Vectorization Based on Lempel-Ziv，Applied Mechanics and Materials Vols. 284-287 (2013) pp 3203-3207 (EI) The 2nd International Conference on Engineering and Technology Innovation 2012 (ICETI2012), November 02-06,2012, Kaohsiung, Taiwan，2013年01月

(59) A Dynamic AdaBoost Algorithm with Adaptive Changes of Loss Function，IEEE Transactions on Systems, Man, and Cybernetics--Part C: Applications and Reviews, 2012,42(6):1828-1841 (SCI, 2011IF=2.009)，2012年12月

(60) Simulation of DNA Replication Based on Discrete Event，2012 IEEE-EMBS Conference on Biomedical Engineering&Sciences, Dec.17, 2012 - Dec.19, 2012, Langkawi, Malasiya (EI)，2012年12月

(61) High Throughput TCR Sequence Alignment Using Multi-GPU with Inter-task Parallelization，2012 IEEE-EMBS Conference on Biomedical Engineering&Sciences, , Dec.17, 2012 - Dec.19, 2012, Langkawi, Malasiya (EI)，2012年12月

(62) Genome-wide control of polyadenylation site choice by CPSF30 in Arabidopsis，Plant Cell, 2012,24(11):4376-4388 (SCI, 2011IF=8.987)，2012年11月

(63) In Silico Prediction of mRNA Poly(A) Sites in Chlamydomonas，Molecular Genetics and Genomics. 2012, 287(11-12):895–907 (SCI, 2011IF=2.635)，2012年11月

(64) Recombinatorial Biases and Convergent Recombination Determine Interindividual TCRβ Sharing in Murine Thymocytes，Journal of Immunology,2012,189(5):2404-2413 (SCI, 2011IF=5.788), published ahead of print July 23, 2012, doi:10.4049/jimmunol.1102087，2012年09月

(65) CMAC-based Sarsa(λ) learning algorithm for RoboCup-soccer goalkeeper，Beijing Gongye Daxue Xuebao/Journal of Beijing University of Technology, 2012,38(9):1348-1352, Language: Chinese (EI)，2012年09月

(66) CBrowse: a SAM/BAM-based contig browser for transcriptome assembly visualization and analysis，Bioinformatics, 2012,28(18):2382-2384 first published online July 12, 2012 doi:10.1093/bioinformatics/bts443 (SCI, 2011IF=5.468)，2012年08月

(67) Identification of Multi-Model LPV Models with Two Scheduling Variables，Journal of Process Control, 2012,22(7):1198-1208 (SCI, 2011IF=1.696)，2012年07月

(68) Some Study on the Identification of Multi-Model LPV Models with Two Scheduling Variables，The 16th IFAC Symposium on System Identification，July 11-13, 2012, Square Brussels Meeting Center, Brussels, Belgium (EI)，2012年07月

(69) An algorithm for resetting PSR models，Jisuanji Xuebao/Chinese Journal of Computers, v 35, n 5, p 1046-1051, May 2012 Language: Chinese(EI)，2012年05月

(70) Pattern analysis approach reveals restriction enzyme cutting abnormalities and other cDNA library construction artifacts using raw EST data，BMC Biotechnology. 2012,12:16 doi:10.1186/1472-6750-12-16 (SCI, 2010IF=2.859)，2012年05月

(71) Characterization and Recognition of mRNA Alternative Polyadenylation Signals，Advanced Science Letters. 2012,9:811-816 (SCI, 2010IF=1.253)，2012年04月

(72) Prediction of Plant Poly(A) Sites Based on GHMM-RWT，Information-An International Interdisciplinary Journal, 2012,15(4):1809-1822 (SCI, 2010IF=0.060).，2012年04月

(73) PATMAP: Polyadenylation site identification from next-generation sequencing data，Lecture Notes in Computer Science, v 7208 LNAI, n PART 1, p 485-496, 7th International Conference, HAIS 2; Salamanca, Spain,2012 (EI)，2012年03月

(74) A method of MPC model error detection，Journal of Process Control, 2012, 22(3):635-642 (SCI, 2010IF=1.655)，2012年03月

(75) High-throughput antibody sequence alignment based on GPU computing，27th Annual ACM Symposium on Applied Computing, SAC 2012 p:1417-1418, March 26, 2012 - March 30, 2012, Trento, Italy (EI)，2012年03月

(76) A novel two-level nearest neighbor classification algorithm using an adaptive，Knowledge-Based Systems, 2012,26:103–110(SCI,2010IF=1.574)，2012年02月

(77) Comprehensive recognition of messenger RNA polyadenylation patterns in plants，African Journal of Biotechnology, 2012, 11(14):3215-3234 (SCI)，2012年02月

(78) Optimization based accurate scheduling for generation and reserve，SCIENCE CHINA Technological Sciences, 2012. 55 (1):223–232 (SCI)，2012年01月

(79) Determinants of public T cell responses，Cell Research, 2012，22(1):33-42 (SCI,2010IF=9.417)，2012年01月

(80) Design and Implementation of RFID-Based Assistant，Advances in Intelligent and Soft Computing, v 137 AISC, p 953-958, 2012, Affective Computing and Intelligent Interaction;Korea,2012 (EI)，2012年01月